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Re: Shortness of breath - New Cortisol Discussion
Posted: Fri May 03, 2013 11:09 am
by ofonorow
randian wrote:ofonorow wrote:I believe it is probably the primary function, although low cortisol may manifest in multiple adverse ways.
Cortisol affects sleep/wake cycles. If your cortisol is low in the morning, you will not wake with energy and vigor like you should. If you have an inverted cortisol curve (low in the morning, high in the evening) you will have difficulty sleeping, and have more energy in the evening than the morning (the opposite of what should happen).
Perhaps. The interesting thing to me is the day your body stops making any cortisol is the last day you will be alive.
So we all make some.
According to Dr. T. Pinkus, cortisol is notoriously hard to measure (and his description reminded my of trying to measure Thyroid hormones).
For me, determining whether a shortage exists is as simple as feeling pain in my joints, especially fingers.
And yes the amount measured during the day follows a certain rhythm, almost opposite to the release of melatonin. Cortisol is low in the morning, increasing during waking hours until a peak around noon.
Re: Shortness of breath - New Cortisol Discussion
Posted: Fri May 03, 2013 2:17 pm
by Johnwen
Re: Shortness of breath - New Cortisol Discussion
Posted: Sat May 04, 2013 2:43 pm
by ofonorow
Re: Shortness of breath - New Cortisol Discussion
Posted: Sat May 04, 2013 3:12 pm
by randian
ofonorow wrote:Lets assume this is proven. That lazy adrenals cannot immediately make up for discontinued cortisol supplementation. I say, then don't stop supplementation!
You certainly shouldn't stop supplementation cold-turkey. A slow weaning is better, if you want to see if your adrenals have "rested" and are ready to take up their regular burden.
Re: Shortness of breath - New Cortisol Discussion
Posted: Sat May 04, 2013 9:55 pm
by Johnwen
Re: Shortness of breath - New Cortisol Discussion
Posted: Sun May 05, 2013 12:51 pm
by ofonorow
Re: Shortness of breath - New Cortisol Discussion
Posted: Sun May 05, 2013 3:02 pm
by Johnwen
What seems to be getting lost is this discussion is that the body can and does loose the ability to make "enough" cortisol, just like the other hormones. When this happens and cortisol is in too short a supply, all sorts of inflammatory ailments begin!
All these High Priced Studies and Articles are incorrect then because of a single book???
Ever hear the saying? Only believe 10% of what you read so you would have to read 10 books to be a believer if they say the same thing. 50% of what you experience so you would have to do it twice and get the same results and if it made you feel good. SOMETHINGS WRONG!
http://www.nlm.nih.gov/medlineplus/ency ... 004000.htmhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791527/http://jcem.endojournals.org/content/89/1/281.fullhttp://www.ncbi.nlm.nih.gov/pubmed/11403980Production levels of cortisol in humans
http://jcem.endojournals.org/content/83 ... ull#sec-10http://www.coreonehealth.com/cortisol-a ... importance
Re: Shortness of breath - New Cortisol Discussion
Posted: Mon May 06, 2013 9:52 am
by ofonorow
Re: Shortness of breath - New Cortisol Discussion
Posted: Mon May 06, 2013 11:52 am
by Johnwen
Re: Shortness of breath - New Cortisol Discussion
Posted: Tue May 07, 2013 12:24 pm
by ofonorow
Re: Shortness of breath - New Cortisol Discussion
Posted: Wed May 08, 2013 10:39 am
by Johnwen
Re: Shortness of breath - New Cortisol Discussion
Posted: Thu May 09, 2013 10:53 am
by ofonorow
Oopps sorry. Now even I am confused!?
Lest summarize where we think we are so far. The medical viewpoint, as exposed by your sir, is that any additional cortisol added exogenously for long periods is bad, or potentially bad.
We both agree that cortisol above and beyond what the body requires to deal with pain is bad.
There are tons of studies and reports about the evils of elevated cortisol.
So my question is whether medicine believes there is a any safe range at all?
I think we can both agree that zero cortisol would be bad. (A person without cortisol would have difficulty living more than 24 hours. This from personal experience.)
Science has identified the normal range of cortisol secretion. That study you cited came very close to what Pincus told me is the known or accepted daily output. Between 8 and 11 mg (in units of oral prednisone).
We agree that any sustained supplementation of more than 11 mg of prednisone is "bad".
If so, then the argument is only regarding a supplemental dosage between 1 mg and 7 mg of prednizone.
I agree that a dosage closer to 1 mg daily is safer than a dosage closer to 7 mg daily.
What I learned from Jefferies is that taking 4 mg does not raise the adrenal secretion above what the brain is requesting. You apparently disagree, and this should be what we are looking for in the science. If the output of a healthy adrenal gland would be 11 mg, Jefferies says taking 4 mg, the adrenal output is then only 7 mg. Because of the hormones released by the brain that control the release of cortisol are reduced as more cortisol circulates in the blood.
Your arguments imply to me that you believe the total cortisol in the body would be 11 mg + the 4 or 15 mg.
I am also trying to make the point that cortisol's primary function is in reducing pain, by reducing inflammation. I have not read, but I think I have discovered that without cortisol, tissues inflame, so low levels of cortisol creates pain and inflammation, which has been called autoimmune diseases and/or disorders. The body apparently attacking itself for no reason.
The reason is hidden by medicines prejudice and bias against cortisol. It apparently never enters a doctors mind that chronic pain, esp. Rheumatoid Arthritis, is caused by deficient levels of cortisol!
And that safe dosages are known, (but apparently not by medical doctors these days), supplemental dosages that can be lowered as the adrenal gland's ability to produce cortisol on their own increases.
Re: Shortness of breath - New Cortisol Discussion
Posted: Fri May 10, 2013 11:44 am
by Johnwen
Re: Shortness of breath - New Cortisol Discussion
Posted: Fri May 10, 2013 1:23 pm
by w6nrw
Absolutely beautiful!
Re: Shortness of breath - New Cortisol Discussion
Posted: Tue May 14, 2013 9:59 am
by Johnwen
Heres a few links to read on the subject.
The first one needs a medscape log in. Join it's free and they e-mail links to you on a subject that intrests the individual.
https://login.medscape.com/login/sso/ge ... DQ5&ac=401This one is open.
http://thehealthscience.com/wiki/Cortic ... g-GlobulinThis is about Cortisols Brother. Just like any other brothers their always Fighting each other.
http://www.encognitive.com/node/12840