Vitamin C Forum

The possible reasoning proposed by the authors was that since the serum proteins are negatively charged in physiological conditions, they may induce liposome aggregation which may get
entrapped when passing through the liver (18)

Not to be distracted

Again to summarize what (I think) we have learned from the innocent "my glucose meter isn't measuring liposomal and AA" post that started this.

A) For whatever reasons, liposomal ingested by mouth diluted in water requires 2 to 3 hours before vitamin C blood levels peak. Corollary) Taking liposomal by mouth without water apparently works much faster.

B) We have measured (and the poster verified), that Ascorbic Acid powder by mouth can peak in as little as 15 minutes (but we didn't wait 2 hours to see if there was another "peak").

C) However, it looks like the viscous phospholipids capture any AA powder, preventing rapid absorption into the blood stream (presumably through the stomach lining) when AA and lipo are taken together.

This is all new information (at least to me) and leads to several questions.

1) Why the delay measuring the liposomal C in the blood?

2) Can we even measure liposomal C in the blood between hours 2 and 3 using the glucose (FREESTYLE LITE) meter?

As an aside, Dr. Hickey made the claim in an otherwise wonderful article on Ebola and Vitamin C recently published in the Townsend Letter

Hickey et al wrote:Liposomal vitamin C is NOT more effective than IV for fighting acute infections.

My wife and I and children have personally experienced the benefits and the curing of numerous coughs and colds. It was I that had the uvulitis. I took 8 spoons at once followed by another 4 spoons 3 hours later, and another 4 spoons 3 hours after that, and the infection literally disappeared! Bear in mind that the uvula had nearly tripled in size and I had called an emergency doctor and was preparing to visit my local hospital A&E(ER).

The ratio of 400/1000:

The volume of a sphere = (4/3)*pi*radius^3.
Surface area of a sphere = = 4*pi*radius^2

That means that the for a 200 nm particle the volume enclosed is 37 times larger than the surface area of the liposome. That means that you need around 27 mg of PC to encapsulate 1000 mg of vitamin c. We use 400 mg so that people get some phosphatidylcholine nutrition.

Our liposomes remain stable in water due to natural forces. This is due to the high ionic strength (large amount of charge) that is on the inside of the liposome. The outside of the liposome remains stable due to the low amount of charge on the outside which allows the hydrophobic components wanting to be together.

For all of these e-mails, I apologize for using equations and mentioning a lot of very technical concepts briefly. Lipid structuring is what I have been doing for over a decade and these types of questions are extremely complicated. Perhaps you and I should come up with some simplified answers that are still scientifically valid.

What is the scientific backing for the statements that LivOnLabs makes?

Best regards,
Emek